Features of EYE ENDRAN

• Recently, various skin boosters with similar ingredients have been released. EYE ENDRAN uses PN ingredients extracted from salmon and is known to have the same PN content as certain original products. PN ingredients extracted from fish other than salmon may have different compositions, so it is advisable to check the source of the raw material. EYE ENDRAN can be a suitable choice for those considering consistent management at a reasonable cost.
• The skin layer depth is adjusted to suit delicate areas from the eyelids to the sides of the eyes, and the embossement procedure is performed.
• PN ingredients are used at their full 2cc volume and are injected without dilution with saline or other solutions.
• Thanks to its thin viscosity, the pain burden during injection may be reduced, and the embossement phenomenon that occurs after the procedure is expected to subside relatively quickly.
• Designed specifically for the delicate eye area, the procedure can be performed gently and comfortably.
• It can be applied not only to the eye area but also to the entire face to help improve skin conditions such as dryness and fine wrinkles. It is generally less painful than typical skin boosters.
• Experienced medical staff focus on precise injection into the dermis layer, and we will also check the eye area's embossement phenomenon with the patient after the procedure.

What is EYE ENDRAN (PN) Skin Booster?

EYE ENDRAN is a skin booster that utilizes PN (Polynucleotide) ingredients specialized for the skin around the eyes.

This procedure can be expected to improve fine wrinkles around the eyes, dull dark circles, and dryness.

It has a similar composition to existing known PN skin boosters and is specifically formulated for the delicate skin around the eyes. It may offer a smoother sensation and relatively less pain during injection, characterized by less prominent embossement.

Why EYE ENDRAN is Necessary for Eye Area Care

The eye area is a very thin and delicate part of the facial skin.

Due to these characteristics, it reacts sensitively to external stimuli, and signs of aging or dryness can appear relatively quickly.

Especially, the skin's protective barrier is prone to weakening, making it common for internal dryness, fine wrinkles, and bluish dark circles to appear simultaneously.

The eye area has a structure with less subcutaneous fat and a thin dermis layer, so general moisturizers or eye creams alone may have limitations.

For these reasons, directly delivering PN ingredients to the dermis layer to induce skin regeneration can be beneficial.

What is the Role of PN (Polynucleotide) Ingredients?

PN is a high-purity, bio-derived ingredient originating from salmon DNA.

Compared to PDRN, PN has a larger molecular weight and is known to have a higher ability to induce a response in the dermis layer and a longer duration for the expected effects.

While PDRN primarily aids in moisturizing and cell recovery, PN can directly act on the dermis layer to contribute to inducing changes in skin structure.

PN can help improve skin health through the following processes:

It can stimulate fibroblasts to promote the production of collagen and elastin. This can contribute to increased skin elasticity, reduction of fine wrinkles, and overall improvement in skin texture.

Increased secretion of various growth factors such as TGF, FGF, and VEGF can aid the skin's natural recovery process and support the regeneration of damaged tissues. Furthermore, it is expected to contribute to calming the skin's inflammatory response and maintaining a healthy state.

It can induce the regeneration of epidermal cells and strengthen the skin barrier. By firming the bonds between keratinocytes, it can help reduce moisture loss and improve internal skin tightness.

The skin barrier is composed like bricks (keratinocytes) and cement (intercellular lipids).

PN can help restore this 'cement' role, inhibiting moisture evaporation from the skin and simultaneously alleviating internal dryness and sensitivity.

Recovery of damaged dermal tissue and increased thickness can be expected. As the thinned dermis layer thickens, it can have a positive impact on reducing dark circles and improving fine wrinkles.

The skin barrier is a structure where keratinocytes and intercellular lipids are combined like bricks and cement. PN ingredients can support the role of this 'cement,' helping to maintain skin moisture and contributing to the improvement of dryness and sensitivity.

Embossement Phenomenon and Dermis Layer Injection Method

The dermis layer has a high tissue density, so the space is relatively narrow.

Therefore, when the medicine is injected into the dermis layer, a temporary convex swelling may appear.

This is called the embossement phenomenon, and it can be an indicator that the medicine has been properly injected into the intended dermis layer.

After the procedure, we will check the embossement phenomenon with the patient and examine the treated area.

During typical PN procedures, the embossement phenomenon may last for several days, but EYE ENDRAN's thin viscosity allows most of it to be absorbed quickly. Furthermore, because the pain burden is relatively low, it can be considered for comfortable treatment even in sensitive areas like the eye contour.

We recommend the EYE ENDRAN procedure for these individuals

• Those who are concerned about the appearance of fine wrinkles around their eyes
• Those who are bothered by bluish dark circles. This may be due to thin skin around the eyes, making blood vessels visible. EYE ENDRAN can help improve dermal thickness, contributing to the reduction of dark circles.
• Those who find their makeup doesn't sit well and their skin texture feels rough due to internal skin tightness
• Individuals with sensitive or thin skin who have felt hesitant about lifting procedures may consider this.
• This can also be helpful for those who feel that daily eye cream use alone is not enough for eye area improvement.
• For those concerned about fine wrinkles on their eyelids but who have hesitated due to the perceived difficulty of the procedure, its applicability can be considered.
• It may also be suitable for those concerned about prominent fine wrinkles right next to the eyes.

Procedure Cycle and Duration of Effect

• Generally, a total of 3 treatment sessions, with a 1-month interval, can be considered.
• After that, touch-up treatments approximately every 6 months can help extend the duration of the effect.
• While there may be differences depending on individual skin conditions, the approximate duration of effect can be expected to be around 6 months to 1 year.
• Pain during the procedure can be minimized, and any embossing marks that appear after the procedure usually subside naturally within 1 to 3 days.

Our Medical Team's Philosophy

Eye area treatments go beyond simply improving visible wrinkles; it is important to focus on activating the skin's inherent regenerative and restorative abilities.

For eye area concerns that were difficult to improve with eye cream alone, the I-Endran procedure has the potential to bring about a new change.

There may come a point when topical skincare alone, applied to the surface of the skin, cannot resolve deeper concerns of the eye area skin.

In such cases, procedures that improve the health and thickness of the skin's dermal layer can be considered.

From this perspective, I-Endran can be an effective starting point for improving eye area skin.

As a medical professional performing skin procedures, it is crucial to focus on the procedure with sincerity and delicacy.

Accurate injection into the treatment area, meticulous verification, and efforts to meet patients' expectations must accompany the process.

Our medical team will accompany you through all these processes and take care of our patients with utmost sincerity.